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English name | 2-Bromo-3-methylthiophene |
English synonyms | Thiophene,2-bromo-3-methyl-;2B3MT;2-BROMO-3-METHYLTHIOPHENE; 2-Bromo-3-Methylthiophene99.Chemicalbook5%;2-bromo-3-methyltiophene; 2-Bromo-3-methylthiophene97%;178.04;2-BROMO-3-METHYLTHIOPHENE98+% |
CAS number | 14282-76-9 |
Molecular formula | C5H5BrS |
Molecular weight | 177.06 |
EINECS number | 238-175-2 |
2-Bromo-3-methylthiophene Chemical Properties | |
Melting point | <25℃ |
Boiling point | 173-176℃(lit.) |
Density | 1.572 g/mL at 25℃(lit.) |
Refractive index | n20/D 1.572(lit.) |
Flash point | 155°F |
Storage conditions | 2-8℃ |
Water solubility | Insoluble in water |
Solubility | Soluble in chloroform, ethyl acetate |
Form | Liquid |
Color | Light yellow low |
Specific gravity | 1.58 |
BRN | 105719 |
CAS database | 14282-76-9(CAS DataBase Reference) |
NIST chemical substance information | Thiophene,2-bromo-3-methyl-(14282-76-9) |
2-Bromo-3-methylthiophene Usage and Synthesis |
Uses |
2-Bromo-3-methylthiophene is used to prepare pyrazolo[3,4-d]pyrimidine derivatives as inhibitors of human enterovirus, coxsackievirus, echovirus, influenza virus, herpes simplex virus, and rhinovirus. It is also used to synthesize oral α7 nicotinic receptor agonists. |
Uses |
New pharmaceutical intermediates. |
Safety Information | |
Hazardous Goods Symbol | T,Xi,Xn |
Hazard Category Code | 25-41-43-36/37/38-20/21/22 |
Safety Instructions | 26-36/37/39-45 |
Hazardous Goods Transport Number | UN 2810 |
WGK Germany | 3 |
Hazard Note | Harmful |
Hazard Level | IRRITANT-HARMFUL,KEEP COLD |
Hazard Level | 6.1 |
Packaging Category | Ⅲ |
Customs Code | 29349990 |
2-Bromo-3-methylthiophene Upstream and downstream product information |
Upstream raw materials |
Acetic acid, acetic anhydride, 3-methylthiophene, N-bromosuccinimide (NBS) |
Downstream products |
2,3,5-trimethylthiophene, 3-methylthiophene-2-boric acid, 3-methylthiophene-2-boric acid ester, 2-BROMOTHIOPHENE-3-CARChemicalbookBALDEHYDE4-Chloro-1-(3-Methyl-2-thienyl)-1-butanone, MTPPA |
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